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Drafted:
NYI / 1999 NHL Entry Draft
Round:
1st (5th overall)
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| Season | Team | GP | G | A | P | +/- | PIM | PP | SH | GW | S | S% |
| 1996-1997 | Syracuse Jr. Crunch-MTJHL | 50 | 42 | 62 | 104 | 34 | ||||||
| 1997-1998 | Erie Otters-OHL | 59 | 30 | 32 | 62 | 32 | ||||||
| 1998-1999 | Erie Otters-OHL | 46 | 34 | 34 | 68 | 50 | ||||||
| 1998-1999 | United States-WJC-A | 6 | 1 | 0 | 1 | 8 | ||||||
| 1999-2000 | Islanders | 81 | 14 | 20 | 34 | -25 | 44 | 2 | 1 | 1 | 114 | 12.3 |
| 2000-2001 | Islanders | 82 | 10 | 31 | 41 | -14 | 42 | 5 | 0 | 0 | 171 | 5.8 |
| 2000-2001 | United States-WC-A | 9 | 3 | 4 | 7 | 4 | ||||||
| 2001-2002 | Sabres | 82 | 10 | 35 | 45 | 4 | 34 | 3 | 0 | 3 | 126 | 7.9 |
| 2002-2003 | Sabres | 80 | 12 | 13 | 25 | -28 | 32 | 6 | 0 | 2 | 159 | 7.5 |
| 2004-2005 | SCL Tigers Langnau-Swiss | 16 | 7 | 3 | 10 | 14 | ||||||
| 2005-2006 | Sabres | 63 | 16 | 39 | 55 | 5 | 28 | 7 | 0 | 3 | 99 | 16.2 |
| 2006-2007 | Sabres | 2 | 1 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 2 | 50.0 |
| 2007-2008 | Sabres | 48 | 7 | 33 | 40 | 4 | 8 | 3 | 1 | 3 | 111 | 6.3 |
| 2008-2009 | Sabres | 48 | 18 | 29 | 47 | 12 | 22 | 5 | 1 | 5 | 126 | 14.3 |
| 2009-2010 | Sabres | 73 | 17 | 48 | 65 | 10 | 28 | 7 | 1 | 5 | 206 | 8.3 |
| 2010-2011 | Sabres | 68 | 13 | 29 | 42 | -10 | 20 | 6 | 0 | 3 | 151 | 8.6 |
| 2011-2012 | Maple Leafs | 70 | 13 | 23 | 36 | -14 | 40 | 2 | 0 | 3 | 104 | 12.5 |
| NHL Totals | 697 | 131 | 300 | 431 | -55 | 300 | 46 | 4 | 28 | 1,369 | 9.6 |
| Season | Team | GP | G | A | P | +/- | PIM | PP | SH | GW | S | S% |
| 1997-1998 | Erie Otters-OHL | 7 | 1 | 6 | 7 | 6 | ||||||
| 2005-2006 | Sabres | 8 | 5 | 6 | 11 | 3 | 0 | 1 | 1 | 1 | 11 | 45.5 |
| 2006-2007 | Sabres | 16 | 0 | 9 | 9 | 6 | 4 | 0 | 0 | 0 | 25 | 0.0 |
| 2009-2010 | Sabres | 6 | 0 | 1 | 1 | -2 | 2 | 0 | 0 | 0 | 16 | 0.0 |
| 2010-2011 | Sabres | 6 | 0 | 2 | 2 | -2 | 2 | 0 | 0 | 0 | 12 | 0.0 |
| NHL Totals | 36 | 5 | 18 | 23 | 5 | 8 | 1 | 1 | 1 | 64 | 7.8 |